Key Topics Covered

This is another podcast episode loosely inspired by a recently published “questions and misconceptions” paper by the ISSN. We have gone with this because it allows us to cover a range of topics. So that way you may get value from one answer or the following question.
Myth: Protein Is Harmful to Your Kidneys
The research consistently finds that high protein diets are not detrimental to kidneys in those who have healthy kidney function at the baseline.
- There have been many studies in the 2-3g/kg range of protein per day with long durations showing no issues with kidney function.
- Higher protein intake vs lower protein intake, within reason, has not been linked with different rates of kidney decline.
- PLUS there isn’t much reason to go higher than 3g/kg.
- Although, the highest protein intake studied was 4.4g/kg for 8 weeks, but while no issues with kidney function were noted, they didn’t track markers as closely as other research, it is also a fairly short study duration.
- If you do NOT have healthy kidneys at the baseline, it’s a bit more complex.
- The authors of this “questions and misconceptions” study highlighted how research on protein restriction for chronic kidney disease has found inconclusive results. This makes it more complicated.
- But for those cases I think a personalised approach with your medical team is necessary, particularly the further progressed it is.
- There is a clinical practice guide for chronic kidney disease that we refer to that lays things out in an evidence-based manner based on individual situations. In there, they build a case for reducing protein intake in very specific cases.
Myth: You Need to Consume Protein ≤ 1 Hour Post-workout for Muscle Growth
Total protein intake matters far more. But if you want to absolutely maximise muscle growth, it is worth having protein within a few hours around the time of your workout (before, after or both).
Do You Need Protein Supplements to Meet the Daily Requirements if You Lift Weights?
- A typical range often recommended for lifters is to aim for 1.6-2.2g/kg for protein.
- This can be met without protein supplements.
- But in some cases it is more convenient to include them.
Can Dietary Protein Have a Harmful Effect on Bone Health?

- This misconception is typically associated with the acid-ash hypothesis, but it is easy to unpack.
- Research consistently finds that those with higher protein intakes tend to have BETTER average bone mineral density.
Is There a Limit to How Much Protein You Can Consume in a Single Meal?
- There is no specific limit.
- Total protein intake is clearly the main priority.
- At minimum, distributing your protein intake helps you consume sufficient total intake and ensures that timing is taken care of without much thought.
- But if you are undercutting your total protein intake to avoid going over a certain gram amount per meal, you are missing the forest for the trees.
Does Consuming “Excess” Protein Increase Fat Mass?
A calorie surplus causes an increase in fat mass. Protein contributes to calorie intake, but it doesn’t directly cause fat gain without the surplus being present.
Myth: You Should Have Casein Before Bed and Whey Post-workout.

The moment you mix whey or casein with anything (e.g. milk or alongside food), the digestion rate slows down to similar rates, defeating the slow-release argument. Research looking at casein post-workout has found similar muscle growth as whey too.
Can Plant-Based Protein Supplements Work as Well as Whey Protein?
- Yes. Some plant-based protein powders are low in relevant amino acids, while others aren’t.
- Some might also have lower digestibility. But if your total protein intake is high enough and you have abundant amino acids, this is not an issue.
- It is all about choosing a good quality option.
- Soy protein isolate has been shown to have a similar anabolic effect and effect on MPS as whey protein.
- Pea and rice blends are also particularly good options.
- Leucine content >2g per serve.
Summary
Hopefully, the answers provided to some of the most popular questions and misconceptions based on protein supplementation are clear and provide you with a better understanding around the science of protein supplementation.
Relevant Links/Resources
Blog posts:
- Does Slow Digesting Protein Before Bed Help Muscle Growth?
- How to Optimise Post-Workout Nutrition
- Protein: What’s Important When Trying to Build Muscle?
- Is High Protein Intake Bad for Kidney Function?
Research:
- Common questions and misconceptions about protein supplementation: what does the scientific evidence really show? – PMC
- KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update – American Journal of Kidney Diseases
- Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion
- Changes in Kidney Function Do Not Differ between Healthy Adults Consuming Higher- Compared with Lower- or Normal-Protein Diets: A Systematic Review and Meta-Analysis
